Understand the stack

AI & LLM Guides

Clear field guides for choosing models, designing workflows, and shipping reliable AI products.

8 entries Newest first
Sep 21, 2026 8 min read

Anthropic Life Sciences Verification Program: A Developer's Guide to Verified AI Deployment in Regulated Life Sciences

Anthropic's newsroom lists a September 17, 2026 announcement for its Life Sciences Verification Program, but the supplied evidence contains no program criteria, access details, or implementation specifications. This guide provides a clearly labeled, framework-agnostic readiness checklist for developers, including integration patterns, evidence packages, hypothetical life sciences workflows, migration controls, and monitoring practices.

Guide
Sep 18, 2026 9 min read

Cohere North Small Translate: A Developer's Guide to Sovereign AI Translation Deployment

The verified source confirms Cohere's blog and a North product link, but it does not substantiate North Small Translate, sovereign translation, deployment, API, performance, or compliance claims. This guide gives developers an evidence-gated way to evaluate the offering without inventing implementation details.

Guide
Sep 14, 2026 9 min read

Open Source vs Open Weight LLMs: A Practical Licensing and Integration Guide

Open source and open weight describe access positions, not automatic permission to use, modify, or redistribute an LLM. This evidence-first guide shows developers how to inventory artifacts, evaluate commercial and redistribution terms, control deployments, and document approval without treating blog labels as legal proof.

Guide
Sep 10, 2026 10 min read

Anthropic Opus 5 Prompting Strategies: A Developer's Guide for Long-Running Coding Agents

Anthropic announced Claude Opus 5 on July 24, 2026 and describes it as an improvement for long-running agents, coding, and professional work. This guide explains how to structure system prompts, user state, assistant responses, tool contracts, recovery loops, context checkpoints, evaluations, and cautious model migration without inventing unsupported model specifications.

Guide
Jul 27, 2026 7 min read

Claude Opus 5 Integration Guide: Building Autonomous Agents with the New Opus Tier

Anthropic announced Claude Opus 5 on July 24, 2026, describing it as a step-change improvement for the Opus tier focused on long-running agents, coding, and professional work. This guide outlines what is known from the official announcement, documents the significant gaps in publicly available technical details, and provides a verification framework for developers preparing to adopt Opus 5 for autonomous workflows. All capability claims are attributed to Anthropic's marketing description and require validation against the full announcement article and API documentation.

Guide
Jul 17, 2026 6 min read

Designing Human-in-the-Loop AI Systems

Place human review where it changes risk: define authority, evidence, escalation paths, feedback quality, and audit records.

Evaluation and Safety
Jul 11, 2026 6 min read

How to Choose the Right LLM for Your Application

A durable, task-first framework for comparing model quality, reliability, latency, privacy, and total operating cost.

Model Selection
Jul 10, 2026 6 min read

How Large Language Models Work

A practical mental model for tokens, attention, training, inference, context, and the limits of generated answers.

LLM Fundamentals